Acute intermittent porphyria : a thesis and 68 publications Upplaga 1
The book includes the thesis and 68 publications of Professor Lennart Wetterberg and a follow-up until 2015 of facts and ideas about the etiology and treatment of the inborn error of metabolism acute intermittent porphyria. Acute intermittent porphyria is a rare disease with abdominal, neurological and psychiatric symptoms. Diagnosis requires biological and genetic testing. Failure to detect an early attack may delay appropriate treatment. Screening of family members is important to identify latent gene carriers, which allows prevention of disease symptoms by avoiding triggering agents. The book illustrates some of the medical problems to be considered in future research e.g. about steroids, oral contraceptives, and melatonin, and the need for novel ways to measure the geno- and phenotypes of individual drug metabolizing enzymes of the cytochrome P450 family. Useful web addresses and author index are also comprised. Several of the reports have previously been published only in Swedish.
Upplaga: 1a upplagan
Utgiven: 2015
ISBN: 9789198075120
Förlag: L & K WHB
Format: Häftad
Språk: Engelska
Sidor: 244 st
The book includes the thesis and 68 publications of Professor Lennart Wetterberg and a follow-up until 2015 of facts and ideas about the etiology and treatment of the inborn error of metabolism acute intermittent porphyria. Acute intermittent porphyria is a rare disease with abdominal, neurological and psychiatric symptoms. Diagnosis requires biological and genetic testing. Failure to detect an early attack may delay appropriate treatment. Screening of family members is important to identify latent gene carriers, which allows prevention of disease symptoms by avoiding triggering agents. The book illustrates some of the medical problems to be considered in future research e.g. about steroids, oral contraceptives, and melatonin, and the need for novel ways to measure the geno- and phenotypes of individual drug metabolizing enzymes of the cytochrome P450 family. Useful web addresses and author index are also comprised. Several of the reports have previously been published only in Swedish.
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